Research Scientist
We are seeking a highly skilled and motivated scientist to join our team. The successful candidate will contribute to our cutting-edge research projects focused on skin microbiome, mucosal immunology and topical drug delivery platforms. This is an exciting opportunity to work in a dynamic and collaborative environment at the forefront of scientific innovation.
Roles and Responsibilities
- Design and execute experiments utilizing gene editing techniques such as CRISPR/Cas9
- Propose and prioritize steps for bacterial strain construction, and systematically trouble-shoot technical hurdles
- Conduct experiments using reconstituted human epithelium (RHE) and animal ex vivo skin models
- Characterize in vitro and in vivo properties of engineered bacterial strains in human skin models
- Conduct immunological and biochemical assays
- Record and present data in well-organized written and oral formats.
- Contribute to study reports and draft manuscripts
- Work effectively in a highly collaborative team environment
Qualifications and Education Requirements
- A background in molecular biology or cell biology and experience in skin physiology and immunology
- Bacterial strain engineering, protein expression and secretion and scale up of protein production
- Familiarity with handling BSL2 bacteria, mammalian cell culture, and sterile technique.
- Experience in the development and performance of biochemical and mammalian/bacterial cell-based assays
- The ability to design, troubleshoot, validate assays, and critically analyze assay data.
- Experience in standard biology techniques such as Western blots, ELISAs, PCR, qPCR
- Familiarity in whole genome sequencing analysis and bioinformatics tool
- PhD or MS + 5 years experience in pharmaceutical research; degree focus in immunology, molecular biology, or cell biology
- Prior experience in skin immunology and/or skin physiology are highly desired. Experience working with skin commensal bacteria is a plus
How to Apply:
