Precision dermatology powered by microbial and genetic engineering
Azitra is a pioneer in genetically engineered bacteria for therapeutic use in dermatology. Our goal is to leverage our platforms and internal microbial library of bacterial strains to create new therapeutics. These treatments are either engineered living organisms or engineered proteins or peptides to treat skin diseases.
We are a clinical-stage biopharmaceutical company focused on precision dermatology, using engineered proteins and live biotherapeutic products. We have built a proprietary platform that includes a microbial library comprised of approximately 1,500 unique bacterial strains that can be screened for unique therapeutic characteristics. The platform is augmented by an artificial intelligence and machine learning technology that analyzes, predicts, and helps screen our library of strains for drug like molecules. The platform also utilizes a licensed genetic engineering technology, which can enable the transformation of previously genetically intractable strains.
Our initial focus is on the development of genetically engineered strains of Staphylococcus epidermidis, or S. epidermidis, which we consider to be an optimal therapeutic candidate species for engineering of dermatologic therapies. The particular species demonstrates a number of well-described properties in the skin, including the ability to instigate reparative, local immune responses. We have identified among our microbial library over 60 distinct bacterial species that we believe are capable of being engineered to create living organisms or engineered proteins with significant therapeutic effect.
Our Leadership Team
Board of Directors
Scientific and Clinical Advisory Board
Julia Oh, PhD
Assistant Professor at The Jackson Laboratory for Genomic Medicine
Leonard Milstone, MD
Professor Emeritus of Dermatology at Yale Medical School
Alain Hovnanian, MD, PhD
Director of Genetics at Necker hospital, Professor of Dermatology, University of Paris
Professor of Molecular Dermatology, Queen Mary University of London
Amy Paller, MD, MSci
Walter J. Hamlin Professor and Chair, Dermatology, Northwestern University